9 Best Wrinkle Fillers, Tested and Recommended by Dermatologists

“Though I have been getting Botox for years, I’ve found that each time I get it (about four times a year) it wears off a little faster each time,” says Brooke.“To help extend the life of my ‘tox and keep my forehead as smooth as possible in between appointments, I started using Skinceuticals P-TIOX Serum after my daily vitamin C serum in the morning and before my retinol products at night.”

This peptide-powered serum made of Skinceuticals’ proprietary blend of advanced peptides and synergistic actives, such as PHA, niacinamide, and laminaria extract, is clinically proven to help reduce fine lines, leaving your skin with a glass-like radiance. “I can confidently say that not only have my expression lines been reduced, but I now wait a little longer between my Botox appointments. I also love how it’s improved the texture of my skin and added a healthy bounce.”

Best for Deep Wrinkles: Strivectin Anti-Wrinkle Peptide Plump Line Filling Bounce Serum

• Pros: Reduces deep wrinkles
• Cons: Takes time to see full results

This product passes the line-filling test with flying colors. “I used this product for a week, and whether it ironed out my wrinkles or not, my skin feels bouncy and looks bright. I love the way it looks, and yes, the forehead lines, which the brand says the serum specifically helps, appear more faint. I would dab on the product in a targeted way, on the problem areas, let it absorb, then put on a layer of moisturizer,” says Glamour contributor Charlotte Twine. Though she says that the wrinkles around her mouth looked about the same, she’s “pleased with the results overall” and plans to make the serum a part of her regular routine.

Best for Eyes: Peter Thomas Roth Peptide Skinjection Fill + Fix Under Eye Cream

• Pros: Smooths out fine lines under the eyes and evens out dark circles almost immediately
• Cons: Temporary effect

“Sometimes there are places that Botox and filler just won’t reach, so to help smooth out my undereyes for the day, I reach for this cream,” says Brooke.“I use it every morning and it not only refreshes the appearance of my tired eyes (because honestly, who’s able to get a full eight hours these days?), but it also helps to color-correct and brighten my under eye area.”. The best part, she adds, is the cooling metal tip that instantly wakes up your eyes and gently spreads the product. “There are times I will use the product alone, without makeup, or I’ll use it prior to applying my foundation. I love it,” she says.

Best Retinol Wrinkle Filler: RoC Retinol Correction Deep Wrinkle Filler

Glamour senior commerce editor Jenifer Calle swears by this RoC product. “Now that I’m in my 30’s retinol has come into play a lot more in my skin care routine, and this wrinkle filler is one of the best creams I’ve tried. I’ve noticed that my skin isn’t as plump and firm as it used to be. Since I’m constantly squinting or looking at my computer, I’ve also noticed I formed ‘elven’ lines on my forehead area. I’ve been using this RoC Retinol Correction Deep Wrinkle Filler on that area of my brows and it significantly reduced the appearance of those lines. I add it to my routine about 1-2 a week and it keeps that area smooth.”

Best Multi-Purpose Wrinkle Filler: Lawless Forget the Filler Skin-Plumping Line-Smoothing Perfecting Cream

• Pros: Works immediately and great under makeup
• Cons: Takes time and consistency for full results

A moisturizer that plumps and also works perfectly as a makeup primer? Say less. “This ultra-soothing pink cream makes my skin look and feel plumped and refreshed almost instantly after application. It’s packed with peptides that help soften fine lines and add bounce and resilience to the skin, and I’ve definitely noticed a difference after using it for a few weeks. The fine lines on my forehead are less apparent and my skin looks tighter and even-toned, not to mention, this cream is perfect for creating a smooth canvas for makeup, too.” says Glamour commerce writer Alanna Martine Kilkeary.

Best Instant Wrinkle Filler: Peter Thomas Roth Instant FIRMx Temporary Face Tightener

• Pros: Goes on smoothly and instantly tightens
• Cons: Filling is temporary

A cult favorite, “this has become my go-to makeup primer as of late,” says Brooke. Formulated with silicones and skin nourishing antioxidants vitamins C and E, the product offers immediate tightening within five minutes of application. The silicone in the formulation “form[s] a thin film over the skin that can fill in the lines and smooth out uneven texture–this is why they’re often found in primers to provide a smooth base for your makeup,” says Dr. Yang.

Though she doesn’t use it every day, Brooke says she reaches for this product when she wants her makeup to look extra smooth on a night out. “I mostly love the tightening effect that it has on my forehead and around my eyes. The only catch is that you have to make sure all your products, such as your moisturizer, are fully absorbed before you even attempt to use this,” she says. “After your face is dry, slowly and smoothly apply the face tightener, keeping your face still and allow it to try before you apply your makeup. Et Voila! Any trouble spots on your face are smooth and your makeup looks flawless,” says Brooke.

Best Budget: No7 Instant Illusion Wrinkle Filler

• Pros: Works instantly
• Cons: Results are temporary